Molecular biologist Prof Jacob Corn describes how gene editing is carried out with CRISPR-Cas9. He explains why this technology has the potential of revolutionizing the treatment of diseases such as sickle cell anemia and malaria. Besides human health, CRISPR-Cas9 can also contribute to improving agriculture and, consequently, food security. Jacob also discusses the possible ethical challenges posed by the widespread application of gene editing. Presented by Dr Andi Horvath.